The Submissive Relationship of Public Health to Government, Politics, and Economics: How Global Health Diplomacy and Engaged Followership Compromise Humanitarian Relief.

This paper describes efforts by public health practitioners to address a health crisis caused by economic development policies that are unrestrained by either environmental, public health, or human rights mandates. Economic development projects funded by international funding institutions like the Inter-American Development Bank that reduce poverty when measured in terms of Gross Domestic Product (GDP) per capita in the transborder region between Suriname and French Guiana harm minority populations where commercial activities destroy, alter, and remove the resources upon which local communities depend. In this study, the structural causes of a community health crisis affecting Indigenous people in the transborder region between Suriname and French Guiana was addressed by seeking gatekeepers in government who have access to policy-making processes. We found that deeply rooted economic development policies structured social, economic, and political alliances and made them resistant to feedback and reform. We concluded that work must be focused beyond the simple exchange of public health information. Public health practitioners must become politically active to create new policy commitments and new patterns of governance that advance development as well as improve health outcomes. Failure to do so may result in public health practitioners becoming 'engaged followers' that are complicit in the inhumanity that springs from their acquiescence to the authority of government officials when their policies are the cause of preventable death, disease, and disability.

Intervention mapping to address social and economic factors impacting indigenous people's health in Suriname's interior region.

BACKGROUND: Previous studies found that while internationally financed economic development projects reduced poverty when measured in terms of per capita GDP, they also caused indigenous people to become disassociated, impoverished and alienated minorities whose health status has declined to unacceptable lows when measured in terms of mercury poisoning and the burgeoning rate of suicide. In this study, we developed a needs assessment and a policy-oriented causal diagram to determine whether the impaired health of the people in this region was at least partially due to the role the country has played within the global economy. Specifically, could the health and well-being of indigenous people in Suriname be understood in terms of the foreign investment programs and economic development policies traceable to the Inter-American Development Bank's Suriname Land Management Project. METHODS: Interviews took place from 2004 through 2015 involving stakeholders with an interest in public health and economic development. A policy-oriented causal diagram was created to model a complex community health system and weave together a wide range of ideas and views captured during the interview process. RESULTS: Converting land and resources held by indigenous people into private ownership has created an active market for land, increased investment and productivity, and reduced poverty when measured in terms of per capita GDP. However, it has also caused indigenous people to become disassociated, impoverished and alienated minorities whose health status has declined to unacceptable lows. While the effects of economic development programs on the health of vulnerable indigenous communities are clear, the governance response is not. The governance response appeared to be determined less by the urgency of the public health issue or by the compelling logic of an appropriate response, and more by competing economic interests and the exercise of power. CONCLUSION: The health and well-being of the indigenous Wayana in Suriname's interior region is at least partially due to the role the country has played within the global economy. Specifically, the health and well-being of indigenous people in Suriname can be understood to be a result of foreign development bank-funded projects that drive the government of Suriname to trade land and natural resources on the global market to manage their country's balance of payments.

Public health programs as surrogates for social action in Suriname, South America.

This paper addresses the merits of public health activism that advocates for social change in which health is the outcome of interest. We acknowledge that while efforts at the individual level are important, social network models consider the underlying mechanisms that lie outside the public health sector. This paper considers the inequitable health of Indigenous people who bear a disproportionate share of the negative health consequences due to economic development programs that follow an assimilation model. This paper discusses a combination of theoretical constructs to understand and solve the problems at hand. It concludes that while the attention paid to technological and behavioral solutions at the individual level yields important health outcomes, attention should also be paid to structural causes that address social, political and economic barriers to prevent disease, disability and premature death.

Neurological abnormalities in a mercury exposed population among indigenous Wayana in Southeast Suriname.

The indigenous Wayana community of Puleowime (Apetina) in Suriname is susceptible to the effects of mercury because they consume large amounts of fish compared to mainstream communities. Small-scale and artisanal gold mining activities occur at numerous sites in eastern and southeastern Suriname placing the Wayana at risk from exposure to mercury released into the environment. A previous community-led risk assessment study showed that the Wayana were at a high lifetime risk of adverse effects from exposure to mercury. Subsequent to this earlier study, the residents of Puleowime requested assistance in a community-led follow-up research project to determine for themselves whether there were health impacts associated with exposure to mercury contamination. Neurotoxic effects consistent with methylmercury exposure were documented in an exposed population through a battery of neurological tests. Although the specific motor and cognitive batteries were not exactly the same, similar associations were observed between neurologic impairment and hair mercury concentrations compared to other studies in the Amazonia region where mean hair mercury levels were in the subacute range.

Implementation of quality improvement skills by primary care teams: case study of a large academic practice.

BACKGROUND: Continuous quality improvement (QI) is important to primary care in general, and is emphasized as a key tenet of the primary care patient-centered medical home (PCMH) model. While team-based QI activities within the PCMH model are expected, concerns exist as to how successful efforts have been at implementing team-driven QI projects. OBJECTIVE: To (a) identify opportunities and challenges to QI efforts in a large primary care practice in order to (b) develop action plans to facilitate QI work into primary care teams. DESIGN: We obtained qualitative and quantitative information about existing primary care team QI initiatives. PARTICIPANTS: Eleven interdisciplinary primary care teams and 4 facilitators/coaches. METHODS: We conducted unstructured interviews and gathered documentation from primary care team members about QI efforts to (a) characterize team-based QI progress and (b) identify barriers and facilitators. RESULTS: In the 18 months since local leadership prioritized conducting team-based QI projects, team members described multiple exposures to QI training, coaching resources, and data/analysis support. No team developed a formal aim statement. Six of the 11 teams completed any steps beyond the initial team discussion. Four teams attempted to apply an intervention. Challenges included team time and competing demands/priorities; 3 of the 4 teams attempting to implement a project credited a data/informatics facilitator for their progress. CONCLUSIONS: In this large academic primary care clinic setting, interdisciplinary team training in QI, support for data collection, and dedicated coaching resources produced few sustainable continuous QI initiatives. Several potentially modifiable barriers to initiation, completion, and sustainability of QI initiatives by primary care teams were identified.

Community-led assessment of risk from exposure to mercury by native Amerindian Wayana in Southeast Suriname.

This study was a collaboration between Western public health researchers and Suriname indigenous communities. The question asked was "how can Western researchers effectively engage traditional indigenous communities in Suriname, South America, in public health research". The approach used a combination of Participatory Action Research methods in which "Western" researchers became participating observers in an indigenous-led research initiative. The Wayana communities of Puleowime (Apetina) and Kawemhakan (Anapayke) defined a single objective: determine for themselves whether they are at risk from exposure to mercury (Hg) contamination. Community members collected hair samples for analysis. Hair samples were analyzed using a portable Hg analyzer. Individual, community and hazard quotient indices were used to quantify risk. Results showed the Wayana were at a high lifetime risk of adverse effects from exposure to Hg. This study showed that the community-led approach is an effective way Westerners can engage indigenous communities and address serious public health threats. While factors that appealed to indigenous communities were identified, obstacles inherent to Western research methodology were also encountered.

Pilot study evaluating a practice-based learning and improvement curriculum focusing on the development of system-level quality improvement skills.

BACKGROUND: We developed a practice-based learning and improvement (PBLI) curriculum to address important gaps in components of content and experiential learning activities through didactics and participation in systems-level quality improvement projects that focus on making changes in health care processes. METHODS: We evaluated the impact of our curriculum on resident PBLI knowledge, self-efficacy, and application skills. A quasi-experimental design assessed the impact of a curriculum (PBLI quality improvement systems compared with non-PBLI) on internal medicine residents' learning during a 4-week ambulatory block. We measured application skills, self-efficacy, and knowledge by using the Systems Quality Improvement Training and Assessment Tool. Exit evaluations assessed time invested and experiences related to the team projects and suggestions for improving the curriculum. RESULTS: The 2 groups showed differences in change scores. Relative to the comparison group, residents in the PBLI curriculum demonstrated a significant increase in the belief about their ability to implement a continuous quality improvement project (P  =  .020), comfort level in developing data collection plans (P  =  .010), and total knowledge scores (P < .001), after adjusting for prior PBLI experience. Participants in the PBLI curriculum also demonstrated significant improvement in providing a more complete aim statement for a proposed project after adjusting for prior PBLI experience (P  =  .001). Exit evaluations were completed by 96% of PBLI curriculum participants who reported high satisfaction with team performance. CONCLUSION: Residents in our curriculum showed gains in areas fundamental for PBLI competency. The observed improvements were related to fundamental quality improvement knowledge, with limited gain in application skills. This suggests that while heading in the right direction, we need to conceptualize and structure PBLI training in a way that integrates it throughout the residency program and fosters the application of this knowledge and these skills.

Benefits and costs of pay for performance as perceived by residents: a qualitative study.

PURPOSE: To describe and interpret pay-for-performance (P4P) systems as perceived by internal medicine residents to develop curricula that relate P4P measures to quality improvement initiatives. METHOD: In 2008-2009, the authors conducted a qualitative study in which 97 internal medicine residents completed a mandatory survey soliciting their views of the advantages and disadvantages of P4P. The authors analyzed responses to identify and categorize emergent themes. RESULTS: Eighty-two residents (85%) noted advantages, from which 13 themes emerged. Two were general themes: P4P improves overall delivery of quality care by enabling quality care and by motivating providers to improve or provide quality care. The other themes formed three categories: P4P enables contemplation and knowledge enhancement (e.g., by promoting reflection) and has potential impacts both on physicians' delivery of better care (e.g., by facilitating vigilance and closer follow-up) and on the care delivery process (e.g., by increasing pay/satisfaction). Eighty-seven residents (90%) indicated disadvantages, from which 16 themes emerged. The four categories of the themes reflected P4P's impacts on patient perceptions (e.g., by decreasing patient satisfaction and access), on clinical care (e.g., by fostering abuse/gaming and compromising focus, care, and safety), on resources and efficiency, and on providers that may undermine morale. CONCLUSIONS: Residents' reported advantages and disadvantages were often in direct opposition to each other (e.g., P4P enables quality care but also compromises focus, care, and safety). These opposing responses form a continuum that the authors believe will require providers to perform a balancing act to practice successfully in a P4P environment.

Teaching quality improvement in the midst of performance measurement pressures: mixed messages?

BACKGROUND: While the importance of teaching quality improvement (QI) is recognized, formal opportunities to teach it are limited and are not always successful at getting physician trainee buy-in. We summarize findings that emerged from a QI curriculum designed to promote physician trainee insights into the evaluation and improvement of quality of care. METHODS: Grounded-theory approaches to thematic coding of responses from 24 trainees to open-ended items about aspects of a QI curriculum. The 24 trainees were subsequently divided into 9 teams that provided group responses to open-ended items about assessing quality care. Coding was also informed by notes from group discussions. RESULTS: Successes associated with QI projects reflected several aspects of optimizing care such as approaches to improving processes and enabling providers. Counterproductive themes included aspects of compromising care such as creating blinders and complicating care delivery. Themes about assessing care included absolute versus process trade-offs, time frame, documentation completeness, and the underrecognized role of the patient/provider dynamic. CONCLUSIONS: Our mapping of the themes provides a useful summary of issues and ways to approach the potential lack of buy-in from physician trainees about the value of QI and the "mixed-messages" regarding inconsistencies in the application of presumed objective performance measures.

Fatal hemolytic anemia associated with metformin: a case report.

INTRODUCTION: Metformin is a widely prescribed biguanide antidiabetic drug that has been implicated as a cause of hemolytic anemia in three previous case reports. We report a case of rapidly fatal hemolysis that was temporally associated with the initiation of metformin treatment for diabetes. Clinicians need to be aware of this rare but potentially serious side effect of metformin. CASE PRESENTATION: A 56-year-old Caucasian man with type 2 diabetes mellitus was started on metformin to improve glycemic control. Shortly afterwards, he developed progressive fatigue, exertional dyspnea, cranberry-colored urine and jaundice. Laboratory studies showed severe hemolysis, with a drop in hemoglobin from 14.7 to 6.6 g/dl over 4 days, markedly elevated lactate dehydrogenase, bilirubin and reticulocyte counts, and a low haptoglobin level. A peripheral blood smear showed no schistocytes, and a direct Coombs test was positive for anti-IgG and negative for anti-C3. Despite corticosteroid treatment and transfusion of packed red blood cells, the patient developed increasing dyspnea, hypotension, further decline in hemoglobin to 3.3 g/dl, and fatal cardiorespiratory arrest 12 hours after admission. CONCLUSION: The serologic findings in this case suggest an autoimmune hemolytic anemia, caused either by a drug-induced autoantibody or a warm autoantibody. Based on the temporal association with metformin and the lack of other clear precipitating causes, we propose that metformin-induced hemolysis with a drug-induced autoantibody is a strong possibility. This mechanism differs from a previously described case with a possible antibody to the erythrocyte-drug complex. It has been shown, however, that hemolysis may occur via multiple mechanisms from the same drug. Clinicians should consider the possibility of metformin-associated immune hemolytic anemia in patients with otherwise unexplained hemolysis.

Pay for performance and medical education: strategies for preparing physicians of the future.

Performance-based reimbursement has become an increasingly important topic in the field of medicine and one that has met with significant legislative support. Small- and large-scale pilot programs in the United States and more comprehensive programs implemented abroad have yielded preliminary findings that raise several interesting questions regarding the form that pay-for-performance programs will take and concerns about the unintended and unforeseen consequences of this new reimbursement approach. One important area that has not been explored, however, is the potential implications of pay for performance to "clinician educators"-individuals from diverse health-related disciplines who both provide health care and are responsible for training the next generation of health care professionals. Because the effect of pay for performance is likely to vary by health care discipline, we focus here on potential implications for physician educators. Our objective is to analyze the experience to date with pay for performance, make predictions from these experiences about the potential impact of pay for performance on the education of resident physicians, and propose educational strategies that might be useful in positioning physician trainees for success as they enter the workforce.

Community-directed risk assessment of mercury exposure from gold mining in Suriname.

OBJECTIVES: The overarching objective of this project was to support the indigenous people in Kwakoegron, Suriname, in self-diagnosis of public and environmental health problems. The specific objectives, defined by the people of Kwakoegron were: (1) to determine for themselves if they are at risk of exposure to mercury (Hg) contamination, (2) to measure the extent of the Hg contamination problem, and (3) to initiate an intervention plan. METHODS: Field work was conducted from June 2005 to April 2006. Community members were trained to collect hair samples for analysis using methods designed to maximize sample quality and consistency and minimize cross-contamination. Each hair sample, of approximately 20 mg, was weighed, added to the sample boat, and analyzed immediately without preservation or storage. Technicians educated in analytical chemistry and trained in the operation of the portable Lumex Zeeman Hg analyzer measured the total Hg (THg) for each hair sample. Confidential meetings were held with each person sampled and any questions were answered. Afterwards, a community meeting was held to reflect on the process, outcome, and future needs. RESULTS: Hair samples from 16 of the 22 participants had Hg levels of 2.2-20.2 microg/g THg, exceeding normal THg levels for hair (2 microg/g THg). During the confidential, individual meetings and the followup community meeting, information was shared regarding the Hg levels found, what the numbers meant scientifically, what the potential health effects could be, and how exposure levels might be brought down. At the conclusion of the followup meeting, the Kwakoegron community proposed an intervention plan that had three principle parts: (1) routine analysis of Hg exposure to monitor trends and track the effects of exposure-reduction efforts; (2) routine health assessments to determine the effects of Hg exposure, particularly in children less than 5 years of age; and (3) fish advisories based on fish biology and trophic level or on the specific measurement of Hg levels in various fish species from various locations and different times throughout the year. CONCLUSIONS: This project showed that a democratic approach to science does not automatically compromise the orderly search for answers. Specifically, our experience in Kwakoegron suggests that the collaborative relationship that emerges by empowering an indigenous community to initiate its own research projects, and address the needs it identifies, can contribute positively to the risk assessment process. This project showed that when Kwakoegron was acknowledged as an equal partner, the risk assessment process led to an open exchange of information and an intervention plan that was both pragmatic and acceptable in the context of the community's unique social and cultural needs.

Community-directed risk assessment of mercury exposure from gold mining in Suriname

OBJECTIVES: The overarching objective of this project was to support the indigenous people in Kwakoegron, Suriname, in self-diagnosis of public and environmental health problems. The specific objectives, defined by the people of Kwakoegron were: (1) to determine for themselves if they are at risk of exposure to mercury (Hg) contamination, (2) to measure the extent of the Hg contamination problem, and (3) to initiate an intervention plan. METHODS: Field work was conducted from June 2005 to April 2006. Community members were trained to collect hair samples for analysis using methods designed to maximize sample quality and consistency and minimize cross-contamination. Each hair sample, of approximately 20 mg, was weighed, added to the sample boat, and analyzed immediately without preservation or storage. Technicians educated in analytical chemistry and trained in the operation of the portable Lumex Zeeman Hg analyzer measured the total Hg (THg) for each hair sample. Confidential meetings were held with each person sampled and any questions were answered. Afterwards, a community meeting was held to reflect on the process, outcome, and future needs. RESULTS: Hair samples from 16 of the 22 participants had Hg levels of 2.2-20.2 µg/g THg, exceeding normal THg levels for hair (2 µg/g THg). During the confidential, individual meetings and the followup community meeting, information was shared regarding the Hg levels found, what the numbers meant scientifically, what the potential health effects could be, and how exposure levels might be brought down. At the conclusion of the followup meeting, the Kwakoegron community proposed an intervention plan that had three principle parts: (1) routine analysis of Hg exposure to monitor trends and track the effects of exposure-reduction efforts; (2) routine health assessments to determine the effects of Hg exposure, particularly in children less than 5 years of age; and (3) fish advisories based on fish biology...

OBJETIVOS: El objetivo central de este proyecto fue apoyar al pueblo indígena de Kwakoegron, Suriname, a hacer su propio diagnóstico de los problemas de salud pública y ambiental. Los objetivos específicos, definidos por la población de Kwakoegron fueron: 1) determinar por sí mismos si están en riesgo de exposición a la contaminación por mercurio (Hg), 2) medir la magnitud del problema de la contaminación con Hg, y 3) comenzar un plan de intervención. MÉTODOS: El trabajo de campo se realizó entre junio de 2005 y abril de 2006. Se entrenó a miembros de la comunidad para tomar muestras de pelo para el análisis mediante métodos diseñados para optimizar la calidad y la consistencia de la muestra y minimizar la contaminación cruzada. Cada muestra de pelo, de aproximadamente 20 mg, se pesó, se colocó en el bote de muestras y se analizó inmediatamente sin conservar o almacenar. Un técnico en química analítica entrenado en la operación del analizador portátil de Hg de Lumex Zeeman midió el Hg total (THg) de cada muestra de pelo. Se realizaron conversaciones confidenciales con cada persona muestreada y se respondieron sus dudas. Luego se realizó una reunión con la comunidad para exponer el proceso, los resultados y las necesidades futuras. RESULTADOS: Las muestras de 16 de los 22 participantes tenían niveles de THg de 2,2-20,2 mg/g, superiores a los niveles normales de THg en pelo (2 mg/g). En las conversaciones confidenciales individuales y en la reunión de seguimiento con la comunidad, se informó sobre los niveles de Hg encontrados, su significado desde el punto de vista científico, los posibles efectos para la salud y cómo se pueden reducir los niveles de exposición. En las conclusiones de la reunión de seguimiento, la comunidad de Kwakoegron propuso un plan de intervención que contaba con tres partes principales: 1) análisis periódicos de la exposición al Hg para monitorear la tendencia y los esfuerzos hechos para reducir la exposición; 2)...

Reducing the rate of amputations in acute diabetic foot infections.

Many older diabetic patients present to the emergency room with limb-threatening foot complications, and may at the same time need attention to life-threatening endocrine, cardiac, or renal complications. To better serve the elderly veteran population at our institution, we designed a multidisciplinary, algorithmic approach that links the podiatry and medicine services to facilitate appropriate referral, admission, and management, with the ultimate goal of reducing the rate of amputations.

Fundamental predictability in multispecies competition: the influence of large disturbance.

Empirical evidence of chaos, or complex behavior, in ecosystems is scarce, presumably due to high system-level noise and/or the rarity of conditions necessary for complex behavior to arise. An alternative explanation might be that complex behavior is fragile and readily suppressed by disturbances that are common in many ecosystems. Here we investigated the role of disturbance frequency and magnitude on complex behavior and focused on population succession trajectories in a plankton system. Because of its prominence in aquatic ecology, we used hydraulic flushing and nutrient loading as disturbances. Our findings from numerical modeling exercises and laboratory microcosm experiments using natural plankton assemblages indicated that one aspect of complex behavior, divergence of nearby trajectories, was suppressed when the magnitude and periodicity of hydraulic flushing and nutrient loading were large. In other words, complex succession became determinable. Divergence of nearby trajectories was relatively robust, however, because pulses of not less than 85% of the total inflow were required to suppress this behavior. Our numerical findings also revealed that large hydraulic disturbances could introduce to the system another aspect of complex behavior, aperiodic succession.